We all love to eat Food even when we are happy, sad or tired. But some of us resist ourselves for eating unhealthy and junk food so that we don’t end up gaining pounds of weight. We think a lot even before having a bite of any sweet dish. But some people eat whatever they want to, at any hour and every type of food and still never gains weight. It’s disheartening to see people shoved food down while the bulges just don’t show.


Why some people never gain weight?

  1. Missing Fat Enzyme

A digestive enzyme that determines how we metabolize fat may be missing in skinny individuals, possibly allowing fat to simply pass through the body without weight gain.

Research suggests that individuals who do not gain weight may actually be missing a crucial digestive enzyme that determines how we metabolize fat.

The fat enzyme, called MGAT2, normally regulates the conversion of fat into energy or into stored fat. Without this enzyme, the body may not store or utilize fat, as it normally would. This would prevent obesity and associated problems like fatty liver disease and glucose intolerance.


  1. Non-exercise activity thermogenesis (NEAT)

Non-exercise activity thermogenesis (NEAT) is the energy expended for everything we do that is not sleeping, eating or sports-like exercise. It ranges from the energy expended walking to work, typing, performing yard work, undertaking agriculture tasks and fidgeting. Even trial physical activities increase metabolic rate substantially and it is the cumulative impact of a multitude of exothermic action that culminate in an individual’s daily NEAT.

NEAT increases with overfeeding and decreases with underfeeding. Thus, NEAT could be a critical component in how we maintain our body weight and develop obesity or loss weight. By understanding how NEAT is regulated we may come to appreciate that spontaneous physical activity is not spontaneous at all but carefully programmed.


  1. Genetic Factors

“Researchers found that a set of genes in chromosome-16 influences body weight, with those having duplication of the chromosome being skinny.”

The term “skinny gene” is not a metaphor after all. Research that appeared in the journal nature reveals that a set of genes in chromosome-16 influences obesity and skinniness.

Most people inherit a pair of chromosome, with one gene from each parent, but there are sometimes duplications or missing chromosomes. In case of duplication of chromosome-16, an individual is unlikely to gain fat, as opposed to people without the gene, who are at greater risk of morbid obesity.


  1. Medical reasons for Thinness

“Undiagnosed health conditions like hyperthyroidism, diabetes, and nutritional disorders can prevent weight gain and require medical attention.”

While there are many individuals who are simply lucky, blessed with the right genes or missing enzymes, others may struggle to gain weight because of undiagnosed health conditions.

So, until scientists can figure out a way to use this knowledge to our advantage and for our eating pleasure, you will just have to go easy on fries and pizzas.



      By -:

      Diksha Tarnekar


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